Disease severity Program

Steering Committee

Meeting Co-Chairs

Glenn T. Furuta, MD

University of Colorado School of Medicine, Children’s Hospital Colorado

Meeting Objectives 

  • Determine key elements of disease severity in EoE patients
  • Assess how to measure disease severity components using a clinically actionable methodology
  • Align stakeholders on a severity index for EoE
  • Discuss future research needs on the impact of severity on treatment and outcomes in EoE
 

Virtual Meeting Agenda

All times listed in Eastern Standard Time.

08:50 AM – 09:00 AM

Meeting Instructions

Session CO-Chairs:

  • Steering Committee

09:00 AM

09:30 AM

Welcome

  • Conference objectives
  • Why EoE needs a severity index
  • Overview of severity indexes for other diseases
  • How do we apply this to EoE

Session CO-Chairs:

Amanda B. Muir, MD

University of Pennsylvania Perelman School of Medicine, Children’s Hospital of Philadelphia

09:50 AM

10:20 AM

Group Discussion to Align on EoE Symptom Severity and Incorporation of Clinical Severity

09:40 AM

09:50 AM

Correlates of Symptom Severity and Outcomes

  • Thresholds for symptoms severity
  • Clinical markers of severity:
    • non-response to treatment
    • multiple atopic conditions
    • growth and nutrition (children); weight loss
    • family history of EoE or strictures
    • mental illness/anxiety/eating disorder
  • Histologic fibrosis (dense or pan esophageal)
  • Recurrent food impaction symptoms in children
  • Decreased esophageal compliance (especially if not reversible or in childhood)

Session CO-Chairs:

Chris A. Liacouras, MD

University of Pennsylvania Perelman School of Medicine, Children’s Hospital of Philadelphia

11:10 AM

11:40 AM

Group Discussion to Align on EoE Endoscopic Severity

Session CO-Chairs:

Dr Dan Atkins

University of Colorado School of Medicine, Children’s Hospital Colorado

12:20 PM

12:50 PM

Group discussion to Align on EoE Histologic Severity

  • Steering Committee and Panel Discussion

02:40 PM

03:00 PM

Closing Remarks and Next Steps

AGA Logo

PRODUCED IN CONJUNCTION WITH KNIGHTEN HEALTH