About EoE

Eosinophilic Esophagitis: Expand, Optimize, Excel

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease that can lead to the narrowing of the esophagus. EoE is one of the most prevalent esophageal diseases worldwide and the leading cause of dysphagia (difficulty swallowing) and food impaction. EoE affects children and adults differently, and diagnosis and treatment are challenging, involving adult and pediatric gastroenterologists, allergists, pathologists and dietitians. Currently, there is a lack of consensus amongst these various health care providers on how to measure overall disease severity in patients with EoE. AGA seeks to address these gaps through its “EoE: Expand, Optimize, Excel” initiative.

This initiative includes medical education, clinical tools and multimedia patient education materials:

EoE Disease Severity Index

The initial program in this initiative, the EoE Disease Severity Consensus Conference held on Aug. 13, 2021 brought together key stakeholders in adult gastroenterology, pediatric gastroenterology, allergy medicine and pathology to align on a severity index for EoE. As awareness increases and new FDA-approved medications become available, the capacity to assess and monitor disease severity will dramatically expand opportunities for improvements in diagnosis and management of patients with EoE. The resulting severity index, the I-SEE, was co-published in the journals Gastroenterology and The Journal of Allergy and Clinical Immunology. Download a PDF copy of the paper here.

EoE Guideline Education

The AGA recruited leaders in EoE to develop and share an accredited educational program to equip practicing gastroenterologists and advanced practice professionals with needed tools and education to help them provide improved, evidence-based care for adult and pediatric patients with EoE.

Project management

The execution of this initiative is supported by Knighten Health LLC, a medical education and communications company founded in 2009. The Knighten Health team are innovators in health education and communication that connect experts and organizations around common interests in health and amplify important medical insights to accelerate improvements in patient care.


This initiative is supported by an independent medical education grant from the Takeda Pharmaceuticals USA, Inc.

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