The AGA launched its “EoE: Expand, Optimize, Excel” initiative to address gaps in provider consensus on EoE disease severity and management and to expand patient awareness of the symptoms, diagnosis, disease severity, and management of EoE. This initiative includes scientific papers, medical education, clinical tools, and multimedia patient education materials

On this page, you can find recent publications relevant to and important for this ongoing initiative: 

Over the past 3 decades, eosinophilic esophagitis (EoE) transformed from a little-known condition to a well-characterized disease often encountered in clinical practice. The Index of Severity for EoE (I-SEE) is now available for you to use as a tool to help assess EoE patients. Developed by a multidisciplinary team of experts, the new tool was published in Gastroenterology. 

Researchers conducted a post-hoc analysis of an 8-week randomized trial comparing two tCS formulations in newly diagnosed EoE patients. I-SEE was calculated at baseline and post-treatment, and patients were classified as mild (1-6 points), moderate (7-14 points), severe (≥15 points), or inactive (0 points). The researchers analyzed clinical, endoscopic, and histologic features at baseline by disease severity, and examined the change in severity before and after treatment, and by histologic response (<15 eos/hpf). 

Elimination diet is an effective treatment for eosinophilic esophagitis (EoE) and offers patients a drug-free alternative to controlling their disease. However, implementing dietary therapy—including careful elimination and systematic reintroduction of potential trigger foods—can be challenging for both patients and clinicians. A new guide published in Clinical Gastroenterology and Hepatology aims to summarize the evidence in support of elimination diets and provides a 50-page dietary resource to help providers successfully implement dietary therapies for EoE.

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