Dr. Spergel is a Professor of Pediatrics at the Perelman School of Medicine at University of Pennsylvania and Chief of the Allergy Section at Children’s Hospital of Philadelphia and director of Center for Pediatric Eosinophilic Disorders and Food Allergy Center.

His research interests have focused on all aspects of food allergy and atopic dermatitis. Some of his important works was the identification that peanut allergy can be outgrown, identification of genetic risk factors for Eosinophilic Esophagitis and the role of basophils in Eosinophilic Esophagitis. He has large role in advocacy and teaching. He has been a member of the medical advisory board for Food Allergy Research and Education (FARE), American Partnership for Eosinophilic Disorders, International Association for Food Protein Induced Enterocolitis and Food Allergy Anaphylaxis Connection Team. He has published over 200 articles in the field. He has spoken national and international in the field of eosinophilic esophagitis, food allergy and atopic dermatitis. He is funded by NIH and multiple foundations. He has conducted over 30 clinical trials in the field of allergy.